
Ovarian Cancer
Ovarian cancer develops silently and is often first detected after it has reached a stage where it can be difficult to treat. The greatest known risk factor for ovarian cancer is a family history of the disease.
deCODEme can calculate your genetic risk for Ovarian Cancer.
The deCODEme Complete Scan implements the latest genetic science to identify a common genetic variant associated with increased risk of developing ovarian cancer.
This new and personalized knowledge can help you and your doctor decide which approach to take to manage your risk for ovarian cancer.
Ovarian cancer is the focus of considerable ongoing research
A focus of current ovarian cancer research is to find new and better methods of detecting the disease early. Some recent studies have focused on improving the definition of ovarian cancer symptoms. Others are looking for ways to make the CA-125 blood test and other diagnostic tests for ovarian cancer more accurate. Recently, researchers have started investigating new methods for early detection, like tumor markers, antibodies, and genetic tests.
deCODEme is proud to offer one of the first genetic risk assessment tests for ovarian cancer
Recently, scientists discovered a common variant on chromosome 9 that can increase a woman’s risk of developing the most common type of ovarian cancer (epithelial cancer) by 13%. This variant is found in approximately 70% of women of European descent (see Song et al, 2009).
The deCODEme Complete Scan identifies this genetic variant and uses it to provide female customers of European descent with a personalized interpretation of their genetic risk for developing ovarian cancer. At present, the necessary scientific information to interpret the genetic risk for women of other ethnicities is not available. This information will be added as soon as it becomes available and we are assured of its quality.
More information
For more information on ovarian cancer, we recommend talking to your doctor and visiting these websites:
For more about clinical trials and ongoing research:
- The Coalition of Cancer Cooperative Groups
- The National Cancer Institute´s Ovarian Cancer Trial Results.
For more about ovarian cancer, genetics, risk factors, symptoms, prevention and treatment:
- All about ovarian cancer from CancerHelp UK
- Staging of ovarian cancer
- International Federation of Gynaecological Oncologists
- Ovarian Cancer from The American Cancer Society
- Myths and facts about ovarian cancer
- Ovarian Cancer Interactive Tutorial from the Patient Education Institute
- FORCE-Facing our Risk of Cancer Empowered
- Genetics and Ovarian Cancer
- Cancer overview – from Caring.com – Helping you help your parents
scientific references
- Jensen A, Sharif H, Frederiksen K, Kjaer SK. Use of fertility drugs and risk of ovarian cancer: Danish Population Based Cohort Study British Medical Journal. 2009 Feb 5;338:b249.
- Song H, Ramus SJ, Tyrer J, Bolton KL, Gentry-Maharaj A, Wozniak E, et al. A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nature Genetics. 2009 Sep;41(9):996-1000. Epub 2009 Aug 2.
This content was last reviewed on February 09, 2010.
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‘We have the ability to test someone’s genetic risk… and then make clinical decisions based on that genetic backdrop.’
Amy L. Doneen A.R.N.P.,
Nurse Practitioner




